Immunohistochemistry in Tumor Diagnostics by Muin S.A. Tuffaha Hans Guski & Glen Kristiansen

Immunohistochemistry in Tumor Diagnostics by Muin S.A. Tuffaha Hans Guski & Glen Kristiansen

Author:Muin S.A. Tuffaha, Hans Guski & Glen Kristiansen
Language: eng
Format: epub
Publisher: Springer International Publishing, Cham


Fig. 14.3CK19 highlighting the cells of papillary thyroid carcinoma. Normal thyroid tissue lacks CK19 expression

Trophoblastic cell surface antigen 2 (Trop-2)

Expression pattern: membranous/cytoplasmic

Main diagnostic use

Expression in other tumors

Expression in normal cells

Papillary thyroid carcinoma, gastrointestinal and pancreatic carcinomas

Carcinomas of the breast, carcinomas of the lung, uterus, uterine cervix and ovaries, bladder, and prostatic carcinoma

Epithelium of salivary glands, pancreas, bile ducts, breast, uterus, prostate, squamous epithelium



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